Lithium orotate is a supplement form of lithium that's sometimes used for brain health and neuroprotection. While there's no direct research specifically linking it to faster or better brain recovery after general anesthesia, some studies and reviews suggest it could potentially help due to its broader protective effects on the brain.

 For instance, low-dose lithium has been shown to stabilize endothelial barriers, reduce neuroinflammation, and promote neural stem cell proliferation, which might aid in recovering from anesthesia-related cognitive fog or temporary impairments like postoperative cognitive dysfunction (POCD). Other sources highlight its role in reversing brain damage, enhancing BDNF (a protein that supports neuron survival), and protecting against memory decline or excitotoxicity, which could indirectly support post-anesthesia normalization. However, these benefits are more commonly discussed in contexts like traumatic brain injury (TBI), depression, or age-related decline rather than anesthesia recovery. Always consult a doctor before using it, as lithium can interact with medications and requires monitoring.Many general anesthetics (like isoflurane, sevoflurane, and desflurane) are fluorinated compounds, but there's no solid evidence they cause permanent cognitive damage specifically due to their fluoride content. General anesthesia can lead to short-term issues like delirium or POCD, especially in the elderly or with repeated exposures, with some studies showing lingering memory or executive function deficits in animal models and a small percentage of humans (e.g., 1-2 years post-surgery in rare cases). These effects are tied to the drugs' impacts on brain signaling (e.g., GABA and NMDA receptors), neuroinflammation, or amyloid/tau pathology in vulnerable people, not fluoride itself. High chronic fluoride exposure from sources like water has been linked to cognitive impairments in some studies (e.g., lower IQ in children or neurological issues), but other research finds no harm at typical levels and disputes permanent damage. Anesthesia involves brief, controlled exposure, so it's unlikely to "hurt cognition forever" via fluoride—most people recover fully.Fluoride can accumulate in the pineal gland (a small brain structure that regulates sleep via melatonin) and contribute to calcification, potentially reducing melatonin output, disrupting sleep, or accelerating puberty in high-exposure scenarios. This is mostly from chronic sources like fluoridated water, not short-term anesthetic use. The "third eye" is a spiritual or esoteric concept associating the pineal with intuition or higher consciousness, but scientifically, there's no evidence fluoride (from any source) targets it in that way—claims about blocking spiritual abilities are unsubstantiated and often tied to conspiracy theories. No studies connect fluorinated anesthetics directly to pineal effects.