diets high in cysteine accelerated regrowth of the small intestine lining after radiation damage.

A study published in Nature on October 1, 2025, led by Fangtao Chi and Ömer H. Yilmaz at MIT, examined how cysteine affects gut healing.

 Experiments in mice showed that diets high in cysteine accelerated regrowth of the small intestine lining after radiation damage.

The team discovered cysteine works by enhancing immune signaling. Specifically, it helps CD8 T cells release IL-22, a protein that activates intestinal stem cells to repair damaged tissue. Mice without IL-22 or CD8 T cells did not recover, even with extra cysteine.

These findings suggest that diet-based strategies could one day support patients recovering from chemotherapy or radiation, potentially improving treatment outcomes.

Bottom Fact : Cysteine promotes gut repair in mice by triggering CD8 T cells to release IL-22, which activates intestinal stem cells.

Source : Nature (October 1, 2025)  Fangtao Chi & Ömer H. Yilmaz, MIT

Disclaimer : This content is for educational purposes. Mouse study results do not directly translate to humans; medical advice and treatment decisions should follow professional guidance.