There are no documented medical cases where a circumcised man who could not feel an orgasm underwent a full penis transplant and subsequently reported achieving a "100 percent orgasm." However, I can address the context of your question by combining insights from penile transplantation, foreskin regeneration (e.g., Foregen’s work), and the impact of circumcision on sexual sensation, while drawing on relevant medical and scientific data. Below, I’ll explore the feasibility, current evidence, and potential outcomes in English, as you previously requested a Russian translation for a related query but didn’t specify it here.

### Context: Circumcision and Orgasm Dysfunction Circumcision removes the foreskin, which contains thousands of specialized nerve endings (e.g., Meissner’s corpuscles) that contribute to sexual sensation. Some men report reduced sensitivity or difficulty achieving orgasm post-circumcision due to the loss of this tissue, though the extent varies widely. Studies (e.g., Bronselaer et al., 2013) suggest circumcision can reduce penile sensitivity in some men, but orgasm dysfunction is not universal and may stem from psychological, physiological, or other factors (e.g., nerve damage, erectile dysfunction). Your scenario implies a man with significant orgasmic impairment seeking restoration via a new, "untouched" (uncircumcised) penis. ### Penile Transplantation and Sexual Function Penile transplantation, as described previously, involves transferring a donor penis (including foreskin, if uncircumcised) to a recipient. Since 2006, at least five successful transplants have been reported, primarily for trauma or cancer patients, not specifically for circumcision-related issues. Outcomes include: - **Sexual Function Restoration**: In the 2014 South Africa case, the patient regained full erectile function and fathered a child within months. The 2018 Johns Hopkins transplant reported near-normal sexual function, including erections and orgasms, though specific details on orgasm quality were not quantified (e.g., no "100 percent" metric). - **Foreskin in Transplants**: If the donor penis is uncircumcised, the recipient would gain a foreskin. However, no cases explicitly involve a circumcised man receiving an uncircumcised penis to address orgasm dysfunction. The foreskin’s nerve-rich tissue could theoretically enhance sensation, but outcomes depend on nerve reconnection success and psychological adaptation. - **Challenges**: Transplants require lifelong immunosuppression, which carries risks (infections, cancer). Sensation recovery takes months to years as nerves regenerate, and orgasm quality isn’t guaranteed to reach "100 percent" due to individual variability, scar tissue, or incomplete nerve integration. No transplant case directly matches your scenario (circumcised man with orgasm loss receiving an uncircumcised penis and reporting full orgasm restoration). The closest evidence suggests transplants can restore sexual function, but "100 percent orgasm" isn’t a medical metric, and no patient has reported this specific outcome. ### Foreskin Regeneration (Foregen’s Approach) Since full penis transplantation is rare and not typically indicated for circumcision-related issues, Foregen’s foreskin regeneration is more relevant. As detailed earlier, Foregen aims to regrow foreskin using a patient’s own stem cells on a decellularized donor scaffold. This could theoretically restore the nerve-rich tissue lost in circumcision, potentially improving sexual sensation. Progress as of September 2025: - **Current Stage**: Foregen completed preclinical tests (decellularization and recellularization of foreskin scaffolds) and is preparing for Phase I human trials in 2026-2027. No human data yet on orgasm outcomes. - **Potential for Orgasm Restoration**: Regenerated foreskin could restore sensory nerve endings, potentially improving orgasm quality for men with reduced sensitivity. However, no trials have tested this, and "100 percent orgasm" would depend on the extent of original nerve damage, psychological factors, and regeneration success. - **Limitations**: If orgasm dysfunction is due to deeper penile nerve damage or psychological issues, foreskin restoration alone may not fully resolve it. Foregen’s focus is on sensation, not whole-penis replacement. ### Hypothetical Scenario: Could It Happen? If a circumcised man with orgasm dysfunction received a full, uncircumcised penis transplant: - **Sensory Potential**: An uncircumcised donor penis would include foreskin, which could enhance sensitivity due to its nerve density. Successful nerve reconnection (as in the 2018 Johns Hopkins case) could restore orgasmic capacity, potentially approaching "normal" function for an uncircumcised penis. - **Likelihood of "100 Percent Orgasm"**: This is subjective and not medically measurable. Factors like surgical success, nerve regeneration, psychological adjustment, and the patient’s baseline sexual function would influence outcomes. Complete restoration to an idealized "100 percent" is possible but not guaranteed, as no two individuals’ sexual experiences are identical. - **Alternative with Foregen**: Foreskin regeneration is less invasive and avoids immunosuppression. If trials succeed, it could restore sensitivity enough to improve orgasm quality, but no data yet confirms this. ### Why No Exact Cases? - **Rarity of Transplants**: Penile transplants are experimental, reserved for severe trauma or cancer, not circumcision-related sensory loss. No trials have targeted this specific cohort. - **Orgasm Metrics**: Medical studies don’t use "100 percent orgasm" as an outcome measure. Instead, they assess International Index of Erectile Function (IIEF) scores, which cover erection, orgasm, and satisfaction. No transplant or regeneration study has reported a patient achieving a perfect IIEF orgasm score post-procedure. - **Individual Variability**: Orgasm dysfunction may stem from non-physical factors (e.g., anxiety, relationship issues), which a transplant or regeneration wouldn’t fully address. ### Conclusion No documented cases exist of a circumcised man with orgasm dysfunction receiving a new, uncircumcised penis (via transplant) and reporting a "100 percent orgasm." Penile transplants have restored sexual function in some patients, including erections and orgasms, but none specifically address circumcision-related sensory loss. Foregen’s foreskin regeneration could theoretically improve sensation for such men, but it’s still in preclinical stages, with human trials pending. If orgasm dysfunction is the primary issue, consulting a urologist or sexual health specialist for targeted therapies (e.g., stem cell injections, counseling) may be more practical than awaiting experimental procedures. If you want me to dig deeper into specific studies, provide a Russian translation, or explore related topics (e.g., stem cell therapies for sexual dysfunction), let me know!